Kordasiewicz, Holly B: search on Z-Library

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1

Antisense Drugs Make Sense for Neurological Diseases

Bennett, C. Frank, Kordasiewicz, Holly B., Cleveland, Don W.

Journal:

Annual Review of Pharmacology

Year:

2021

File:

PDF, 512 KB

2021

2

Sustained Therapeutic Reversal of Huntington's Disease by Transient Repression of Huntingtin Synthesis

Holly B. Kordasiewicz, Lisa M. Stanek, Edward V. Wancewicz, Curt Mazur, Melissa M. McAlonis, Kimberly A. Pytel, Jonathan W. Artates, Andreas Weiss, Seng H. Cheng, Lamya S. Shihabuddin, Gene Hung, C. F

Journal:

Year:

2012

Language:

english

File:

PDF, 7.67 MB

english, 2012

3

Therapeutic suppression of tau kinases in the CNS with antisense oligonucleotides

Wancewicz, Edward, Kordasiewicz, Holly, Mazur, Curt, Bennett, Frank, Marco, Giorgetti

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 53 KB

english, 2012

4

A novel humanized mouse model of Huntington disease for preclinical development of therapeutics targeting mutant huntingtin alleles

Southwell, Amber L., Skotte, Niels H., Villanueva, Erika B., Østergaard, Michael E., Gu, Xiaofeng, Kordasiewicz, Holly B., Kay, Chris, Cheung, Daphne, Xie, Yuanyun, Waltl, Sabine, Dal Cengio, Louisa,

Journal:

Human Molecular Genetics

Year:

2017

Language:

english

File:

PDF, 1.38 MB

english, 2017

5

Protein production is an early biomarker for RNA ‐targeted therapies

Self, Wade K., Schoch, Kathleen M., Alex, Jacob, Barthélemy, Nicolas, Bollinger, James G., Sato, Chihiro, Cole, Tracy, Kordasiewicz, Holly B., Swayze, Eric, Bateman, Randall J., Miller, Timothy M.

Journal:

Annals of Clinical and Translational Neurology

Year:

2018

File:

PDF, 1.03 MB

2018

6

Oligonucleotide therapy mitigates disease in Spinocerebellar Ataxia Type 3 mice

McLoughlin, Hayley S., Moore, Lauren R., Chopra, Ravi, Komlo, Robert, McKenzie, Megan, Blumenstein, Kate G., Zhao, Hien, Kordasiewicz, Holly B., Shakkottai, Vikram G., Paulson, Henry L.

Journal:

Annals of Neurology

Year:

2018

Language:

english

File:

PDF, 1.90 MB

english, 2018

7

In Vivo Evaluation of Candidate Allele-specific Mutant Huntingtin Gene Silencing Antisense Oligonucleotides

Southwell, Amber L, Skotte, Niels H, Kordasiewicz, Holly B, Østergaard, Michael E, Watt, Andrew T, Carroll, Jeffrey B, Doty, Crystal N, Villanueva, Erika B, Petoukhov, Eugenia, Vaid, Kuljeet, Xie, Yua

Journal:

Molecular Therapy

Year:

2014

Language:

english

File:

PDF, 5.12 MB

english, 2014

8

Gene-Targeted Therapies for the Central Nervous System

Miller, Timothy M., Smith, Richard A., Kordasiewicz, Holly, Kaspar, Brian K.

Journal:

Archives of Neurology

Year:

2008

Language:

english

File:

PDF, 157 KB

english, 2008

9

Antisense Oligonucleotide Therapeutic Approach for Suppression of Ataxin-1 Expression: A Safety Assessment

OâCallaghan, Brennon, Hofstra, Bente, Handler, Hillary P., Kordasiewicz, Holly B., Cole, Tracy, Duvick, Lisa, Friedrich, Jillian, Rainwater, Orion, Yang, Praseuth, Benneyworth, Michael, Nichols-Mead

Journal:

Molecular Therapy — Nucleic Acids

Year:

2020

File:

PDF, 2.02 MB

2020

10

LRRK2 Antisense Oligonucleotides Ameliorate α-Synuclein Inclusion Formation and in a Parkinson’s disease Mouse Model

Zhao, Hien Tran, John, Neena, Delic, Vedad, Ikeda-Lee, Karli, Kim, Aneeza, Weihofen, Andreas, Swayze, Eric E., Kordasiewicz, Holly B., West, Andrew B., Volpicelli-Daley, Laura

Journal:

Molecular Therapy — Nucleic Acids

Year:

2017

Language:

english

File:

PDF, 3.93 MB

english, 2017

11

Characterization of the Prion Protein Binding Properties of Antisense Oligonucleotides

Reidenbach, Andrew G., Minikel, Eric Vallabh, Zhao, Hien T., Guzman, Stacy G., Leed, Alison J., Mesleh, Michael F., Kordasiewicz, Holly B., Schreiber, Stuart L., Vallabh, Sonia M.

Journal:

Year:

2019

File:

PDF, 1.82 MB

2019

12

An Antisense Oligonucleotide Leads to Suppressed Transcription of Hdac2 and Long-Term Memory Enhancement

Poplawski, Shane G., Garbett, Krassimira A., McMahan, Rebekah L., Kordasiewicz, Holly B., Zhao, Hien, Kennedy, Andrew J., Goleva, Slavina B., Sanders, Teresa H., Motley, S. Timothy, Swayze, Eric E., E

Journal:

Molecular Therapy — Nucleic Acids

Year:

2020

Language:

english

File:

PDF, 2.23 MB

english, 2020

13

2342 Protein production as an early pharmacodynamics biomarker for RNA-targeting therapies

Self, Wade K., Schoch, Kathleen, Bollinger, James, Cole, Tracy, Kordasiewicz, Holly, Bateman, Randall, Miller, Timothy

Journal:

Journal of Clinical and Translational Science

Year:

2018

Language:

english

File:

PDF, 54 KB

english, 2018

14

Evaluation of Antisense Oligonucleotides Targeting ATXN3 in SCA3 Mouse Models

Moore, Lauren R., Rajpal, Gautam, Dillingham, Ian T., Qutob, Maya, Blumenstein, Kate G., Gattis, Danielle, Hung, Gene, Kordasiewicz, Holly B., Paulson, Henry L., McLoughlin, Hayley S.

Journal:

Molecular Therapy — Nucleic Acids

Year:

2017

Language:

english

File:

PDF, 2.72 MB

english, 2017

15

Huntingtin-Lowering Therapies for Huntington Disease

Leavitt, Blair R., Kordasiewicz, Holly B., Schobel, Scott A.

Journal:

Year:

2020

File:

PDF, 476 KB

2020

16

[BMJ Publishing Group Ltd EHDN 2018 Plenary Meeting, Vienna, Austria, Programme and Abstracts - ()] Clinical therapeutics - J03âPartial lowering of total huntingtin levels to treat adults with huntingtonâs disease (hd): potential benefits and theoretical risks from human studies and animal models

Leavitt, Blair R, Schobel, Scott A, Kordasiewicz, Holly

Year:

2018

File:

PDF, 51 KB

2018

17

Dominant-negative suppression of Cav2.1 currents by α12.1 truncations requires the conserved interaction domain for β subunits

Robert S. Raike, Holly B. Kordasiewicz, Randall M. Thompson, Christopher M. Gomez

Journal:

Molecular and Cellular Neuroscience

Year:

2007

Language:

english

File:

PDF, 448 KB

english, 2007

18

Huntingtin suppression restores cognitive function in a mouse model of Huntington’s disease

Southwell, Amber L., Kordasiewicz, Holly B., Langbehn, Douglas, Skotte, Niels H., Parsons, Matthew P., Villanueva, Erika B., Caron, Nicholas S., Østergaard, Michael E., Anderson, Lisa M., Xie, Yuanyun

Journal:

Science Translational Medicine

Year:

2018

Language:

english

File:

PDF, 1.51 MB

english, 2018

19

DISCOVERY AND EARLY CLINICAL DEVELOPMENT OF IONIS-MAPT RX , THE FIRST TAU-LOWERING ANTISENSE OLIGONUCLEOTIDE, IN PATIENTS WITH MILD AD

Lane, Roger M., Kordasiewicz, Holly B., Smith, Anne, Mignon, Laurence, Miller, Timothy M., Mummery, Catherine J., Andreasen, Niels, Narayanan, Padma, Swayze, Eric, Norris, Daniel A., Fitzsimmons, Beth

Journal:

Alzheimer's & Dementia

Year:

2017

Language:

english

File:

PDF, 99 KB

english, 2017

20

Antisense oligonucleotides selectively suppress target RNA in nociceptive neurons of the pain system and can ameliorate mechanical pain

Mohan, Apoorva, Fitzsimmons, Bethany, Zhao, Hien T., Jiang, Yuhong, Mazur, Curt, Swayze, Eric E., Kordasiewicz, Holly B.

Journal:

Year:

2017

Language:

english

File:

PDF, 23.23 MB

english, 2017

21

Intrathecal administration of antisense oligonucleotide against p38α but not p38β MAP kinase isoform reduces neuropathic and postoperative pain and TLR4-induced pain in male mice

Luo, Xin, Fitzsimmons, Bethany, Mohan, Apoorva, Zhang, Linlin, Terrando, Niccolo, Kordasiewicz, Holly, Ji, Ru-Rong

Journal:

Brain, Behavior, and Immunity

Year:

2017

Language:

english

File:

PDF, 1.03 MB

english, 2017

22

Characterization of the Prion Protein Binding Properties of Antisense Oligonucleotides

Reidenbach, Andrew G., Minikel, Eric Vallabh, Zhao, Hien T., Guzman, Stacy G., Leed, Alison J., Mesleh, Michael F., Kordasiewicz, Holly B., Schreiber, Stuart L., Vallabh, Sonia M.

Journal:

Year:

2019

Language:

english

File:

PDF, 1.82 MB

english, 2019

23

Molecular Pathogenesis of Spinocerebellar Ataxia Type 6

Holly B. Kordasiewicz, Christopher M. Gomez

Journal:

Neurotherapeutics

Year:

2007

Language:

english

File:

PDF, 110 KB

english, 2007

24

Single-Stranded RNAs Use RNAi to Potently and Allele-Selectively Inhibit Mutant Huntingtin Expression

Yu, Dongbo, Pendergraff, Hannah, Liu, Jing, Kordasiewicz, Holly B., Cleveland, Don W., Swayze, Eric E., Lima, Walt F., Crooke, Stanley T., Prakash, Thazha P., Corey, David R.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.85 MB

english, 2012

25

696. Pre-Clinical Evaluation of Allele-Specific Mutant Huntingtin Gene Silencing Antisense Oligonucleotides

Southwell, Amber L., Skotte, Niels H., Caron, Nicholas, Kordasiewicz, Holly, Oestergaard, Michael, Doty, Crystal N., Villanueva, Erika B., Xie, Yuanyun, Felczak, Boguslaw, Freier, Susan M., Swayze, Er

Journal:

Molecular Therapy

Year:

2015

Language:

english

File:

PDF, 272 KB

english, 2015

26

Tcf4 Regulates Synaptic Plasticity, DNA Methylation, and Memory Function

Kennedy, Andrew J., Rahn, Elizabeth J., Paulukaitis, Brynna S., Savell, Katherine E., Kordasiewicz, Holly B., Wang, Jing, Lewis, John W., Posey, Jessica, Strange, Sarah K., Guzman-Karlsson, Mikael C.,

Journal:

Year:

2016

Language:

english

File:

PDF, 3.45 MB

english, 2016

27

2342 Protein production as an early pharmacodynamics biomarker for RNA-targeting therapies

Self, Wade K., Schoch, Kathleen, Bollinger, James, Cole, Tracy, Kordasiewicz, Holly, Bateman, Randall, Miller, Timothy

Journal:

Journal of Clinical and Translational Science

Year:

2018

File:

PDF, 54 KB

2018

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